Panbonis®: the unique, safe, and natural source of the bioactive form of vitamin D3

  • Improves calcium and phosphorus metabolism

  • Improves eggshell quality

  • Increases the number of saleable eggs

  • Improves FCR

  • Helps to reach 500 eggs per hen housed

  • Improves fertility

  • Improves piglet vitality and litter homogeneity

  • Shortens parturition time

Panbonis® is a complementary feed that contains a standardized level of 1,25 dihydroxycholecalciferol-glycosides (1,25(OH)2D3-gly) from dried and ground Solanum glaucophyllum leaves.

1,25(OH)2D3-gly can only be absorbed after the sugar molecule is released from 1,25(OH)2D3 by specific enzymes that are present in the intestine. This gradual process ensures a slow release of the bioactive component. Once absorbed, it does not need additional activation steps like vitamin D3 or 25-hydroxycholecalciferol (25(OH)D3) do, which means that Panbonis® can directly support the animal even when specific activation enzymes in liver and kidney are limited.

  • Supports the crucial role of vitamin D3

  • 100% Natural

  • GMO-free

  • Standardized content of the active ingredient

  • Gradually absorbed from the intestine

  • Considered a complementary feed in the EU

  • High processing and storage stability

Vitamin D3 (metabolites) in animal feed

The following three vitamin D3 metabolites can be used to supplement animal feed:

  1. Vitamin D3- the most common source

  2. 25-hydroxycholecalciferol (25(OH)D3)- either produced in a chemical process or through fermentation

  3. 1,25-dihydroxycholecalciferol-glycosides (1,25(OH)2D3-gly)- an entirely natural source of the bioactive form of vitamin D3

Some characteristics of the vitamin D3 and its metabolites, as used in animal nutrition, are summarised in Table 1.

  Vitamin D3 25(OH)D3 Panbonis®
Principal molecule Vitamin D3 25(OH)D3 1,25(OH)2D3-gly
Solubility Fat-soluble Fat-soluble Water-soluble
Enzymatic activation steps 2 steps: In liver and kidney 1 step: In kidney No activation needed: Cleavage of glycosides in the intestine

From Vitamin D3 to the active metabolite

Product characteristics

  • Heat stable during feed processing (expender, pelleting and expander-pelleting)

  • Shelf life: 24 months, when stored in a dry place at room temperature

  • Particle size: 0.2mm; >90% between 0.05 – 1.6mm

  • Packaging: 20kg bags

  • Available for organic production, too

The general dosage is 50 - 200g of Panbonis® 10 per ton of feed, providing 0,5-2µg of 1,25(OH)2D3 -equivalents/kg of feed. Because it is supplied in addition to the usual supplementation level of vitamin D3, there is no need to adjust the premix.

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