Panbonis®: the unique, safe, and natural source of the bioactive form of vitamin D3
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Improves calcium and phosphorus metabolism
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Improves eggshell quality
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Increases the number of saleable eggs
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Improves FCR
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Helps to reach 500 eggs per hen housed
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Improves fertility
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Improves piglet vitality and litter homogeneity
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Shortens parturition time
Panbonis® is a complementary feed that contains a standardized level of 1,25 dihydroxycholecalciferol-glycosides (1,25(OH)2D3-gly) from dried and ground Solanum glaucophyllum leaves.
1,25(OH)2D3-gly can only be absorbed after the sugar molecule is released from 1,25(OH)2D3 by specific enzymes that are present in the intestine. This gradual process ensures a slow release of the bioactive component. Once absorbed, it does not need additional activation steps like vitamin D3 or 25-hydroxycholecalciferol (25(OH)D3) do, which means that Panbonis® can directly support the animal even when specific activation enzymes in liver and kidney are limited.
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Supports the crucial role of vitamin D3
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100% Natural
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GMO-free
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Standardized content of the active ingredient
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Gradually absorbed from the intestine
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Considered a complementary feed in the EU
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High processing and storage stability
Vitamin D3 (metabolites) in animal feed
The following three vitamin D3 metabolites can be used to supplement animal feed:
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Vitamin D3- the most common source
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25-hydroxycholecalciferol (25(OH)D3)- either produced in a chemical process or through fermentation
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1,25-dihydroxycholecalciferol-glycosides (1,25(OH)2D3-gly)- an entirely natural source of the bioactive form of vitamin D3
Some characteristics of the vitamin D3 and its metabolites, as used in animal nutrition, are summarised in Table 1.
| Vitamin D3 | 25(OH)D3 | Panbonis® | |
|---|---|---|---|
| Principal molecule | Vitamin D3 | 25(OH)D3 | 1,25(OH)2D3-gly |
| Solubility | Fat-soluble | Fat-soluble | Water-soluble |
| Enzymatic activation steps | 2 steps: In liver and kidney | 1 step: In kidney | No activation needed: Cleavage of glycosides in the intestine |
From Vitamin D3 to the active metabolite
Product characteristics
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Heat stable during feed processing (expender, pelleting and expander-pelleting)
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Shelf life: 24 months, when stored in a dry place at room temperature
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Particle size: 0.2mm; >90% between 0.05 – 1.6mm
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Packaging: 20kg bags
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Available for organic production, too
Dosage:
The general dosage is 50 - 200g of Panbonis® 10 per ton of feed, providing 0,5-2µg of 1,25(OH)2D3 -equivalents/kg of feed. Because it is supplied in addition to the usual supplementation level of vitamin D3, there is no need to adjust the premix.
Contact us to find customized information.
FAQs
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What is Panbovine®?
Panbovine® is a granulated form of waxy-leaf nightshade meal (Solanum glaucophyllum).
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What is the difference between Panbovine® and Panbonis®?
Panbovine® is a microencapsulated product of micronized Solanum glaucophyllum leaves with a specific regular granulometry, free-flowing, especially adapted for the bolus manufacturing.
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What is the regulatory status of Panbovine®?
The regulatory status of Panbovine® depends on the country. Please contact our team to get more information.
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Why did Herbonis develop Panbovine®?
Panbovine® was developed to serve the dairy industry with an optimal product for bolus application in dairy cows.
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What is the active component in Solanum glaucophyllum?
Glycosylated 1,25-dihydroxycholecalciferol (G-1,25(OH)2D3) is naturally occurring in the plant Solanum glaucophyllum and represents a unique source of the active form of vitamin D.
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How does Panbovine® support the Calcium metabolism?
Vitamin D is a key factor in the regulation of the calcium metabolism. Vitamin D3 is converted in the liver and then the kidney to first 25-hydroxyvitamin D3 and then to its active form 1,25-dihydroxycholecalciferol (1,25(OH)2D3). In Panbovine®, 1,25(OH)2D3 is present as glycoside. After cleavage of the glycosides in the rumen, the free 1,25(OH)2D3 is absorbed and supports the cow in maintaining the serum Ca-concentration around calving.
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What is the recommended application?
Panbovine® should be supplied through a bolus.
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Can a claim be made on the prevention on hypocalcemia/milk fever?
In the EU, waxy-leaf nightshade meal is listed in Regulation (EU) 2020/354 establishing feed for particular nutritional use (PARNUT) reducing the risk of milk fever and subclinical hypocalcaemia.