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  • Scientific Paper (11)
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  • Ruminant (6)
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Article Poultry

EGGCELLENT - Cracking Eggshell Quality in Ageing Laying Hens

Interplay of vitamin D, calcium, and phosphorus metabolism in eggshell formation.

Herbonis Animal Health GmbH
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Article Poultry

Activated vitamin D: Connecting parents and offspring

Good chick quality and the number of fertile settable eggs per hen housed are the main drivers in broiler breeder operations. Apart from incubation conditions, successful hatchability depends on many factors related to eggshell quality (for example strength, porosity and absence of microfractures).

by Katia Pedrosa and Kathrin Buehler, Herbonis Animal Health GmbH
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Article Poultry

Understanding the lack of 1,25(OH)2 vitamin D3 in aged laying hens

During the last decade, great progress has been made on the laying persistency of white and brown laying hens. As a result, there is an increasing number of flocks that pass the ‘500 eggs milestone’ in many countries. This milestone is better known as ‘500 eggs per hen housed without moulting’.

by Jan Dirk van der Klis and Katia Pedrosa, Herbonis Animal Health GmbH
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Scientific Article Poultry

A beat of science 004: Heat stress in laying hens

The combination of high ambient temperatures and high humidity is a well-known external stressor in livestock production. Layers are particularly sensitive to heat stress, because of daily egg and eggshell production.

Herbonis Animal Health GmbH
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Article Poultry

Natural vitamin D3 metabolite supports bone health of laying hens

Proper skeleton calcium (Ca) stores is key to reduce bone disorders. Early sexual maturation, alongside production of the first egg at a younger age, fast increase to peak production and improved laying persistency, has increased the demand for proper skeletal Ca stores at the start of egg production. Only then can bone and shell quality be maintained …
Katia Pedrosa & Jan Dirk Van der Klis, Herbonis Animal Health GmbH
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Article Poultry

Solanum glaucophyllum in layer hen diets to reduce dietary phosphorus

Modern laying hens have a huge potential to produce affordable and high quality animal protein. In current practice, layers can produce over 500 eggs per hen-housed, whereas the potential of certain genetics under optimal conditions is already at least 30% higher.

by Jan Dirk van der Klis and Kathrin Buehler, Herbonis Animal Health GmbH
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Scientific Paper Poultry

Bone characteristics of broiler chickens fed diets supplemented with Solanum glaucophyllum

The aim of this study was to assess the characteristics of the tibiotarsus of male broilers at 21 and 35 days of age. The percentages of collagenous proteins (CP), non-collagenous proteins (NCP), ash, and minerals (calcium, phosphorus, potassium and sodium), as well as weight of dried and defatted tibiotarsus in natura were determined.

Vieites, Droshgic, Souza, Vargas Junior, Nunes, Kling de Moraes, da Silva Salles Correa, Caramori Junior
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Scientific Paper Poultry

1,25-dihydroxycholecalciferol from Solanum glaucophyllum supports normal growth and reduces the negative effects of calcium and phosphorus restriction on broilers’ bone tissue

Feed supplementation with 1,25-dihydroxycholecalciferol (1,25(OH)2D3) has been studied as a means to decrease the incidence of bone abnormalities in broilers and reduce dietary inclusion of calcium and phosphorus. The objective of this research was to determine the optimal level of feed supplementation with 1,25(OH)2D3 from Solanum glaucophyllum for growing …
Feed supplementation with 1,25-dihydroxycholecalciferol (1,25(OH)2D3) has been studied as a means to decrease the incidence of bone abnormalities in broilers and reduce dietary inclusion of calcium and …
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Scientific Paper Poultry

Safety profile of 1,25-dihydroxyvitamin D3 of herbal origin in broiler chicken

The safety of supplementing broiler feed with a standardised herbal extract, Solanum Glaucophyllum Standardised Leaves (SGSL) containing glycosylated 1α,25-dihydroxyvitamin D3 (1,25(OH)2D3) and standardised to contain …

Mathis, Boland, Bachmann, Toggenburg
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Scientific Paper Poultry Ruminant Swine Aqua

Vitamin D: Classic and Novel Actions

Background: Classically, vitamin D has been implicated in bone health by promoting calcium absorption in the gut and maintenance of serum calcium and phosphate concentrations, as well as by its action on bone growth and reorganization through the action of osteoblasts and osteoclasts cells.

Gil, Plaza-Diaz, Mesa
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Abstract Poultry Ruminant Swine Aqua

Consequences of genetic selection on metabolic regulation of skeletal health in broiler chickens

Improvements in broiler growth performance resulting from commercial selection are associated with poor skeletal health. Vitamin D3 plays an important role in Ca and P homeostasis and is essential for bone strength. Several studies have demonstrated that feeding biologically active metabolites of D3 [25(OH)D3 and 1,25(OH)2D3] can improve bone health.

Ellestad, Payne, Marhsal, Boothby
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Scientific Paper Poultry

Studies on the Efficacy of Cholecalciferol and Derivatives for Stimulating Phytate Utilization in Broilers

Studies were conducted to determine the effect of dietary supplementation with cholecalciferol (D3), 1,25-dihydroxycholecalciferol [1,25-(OH)2D3], 1alpha-hydroxycholecalciferol (1α-OHD3), and 25-hydroxycholecalciferol (25-OHD3) on utilization of phytate P by broiler chickens.

Edwards
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Abstract Poultry

Difference in time to action between a 1α,25 (OH)2D3-glycoside containing extract of Solanum glaucophyllum and Vitamin D in Japanese quails

The plant Solanum glaucophyllum (SG) is known to contain 1α,25-Dihydroxycholecalciferol in a glycosidic form (1α,25(OH)2D3-Gly). Products derived from this plant can therefore be used to support the functions of Vitamin D (VD) in men and animal.

Bühler, Bachmann, Rambeck
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Scientific Paper Poultry Ruminant Swine Aqua

1,25-Dihydroxyvitamin D3-glycoside of herbal origin exhibits delayed release pharmacokinetics when compared to its synthetic counterpart

Vitamin D requires two metabolic steps to become biologically active. In a first step 25-hydroxyvitamin D3 is formed, which acts as storage form. After a tightly controlled step in kidney the active metabolite 1,25-dihydroxyvitamin D3 (1,25(OH)2D3) is formed. Because kidney is the relevant metabolic organ for this conversion, 1,25(OH)2D3 needs …

1982 - Bachmann, Offord-Cavin, Phothirat, Horcajada, Romeis, Mathis
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Scientific Paper Poultry

The effectiveness of a new standardized Solanum glaucophyllum preparation for optimizing bone quality in broilers.

Vitamin D is essential in modern poultry production. However, the classical form cholecalciferol (VD3) may not to suffice for optimal bone health in fast growing poultry because it needs two metabolic steps to become active. Supplementation with the active form 1,25- dihydroxyvitamin D3 (1,25(OH) 2D3) has been found to be the most effective means for …
Bachmann, McCormack, Whitehead
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Scientific Paper Poultry

The efficacy of a standardised product from dried leaves of Solanum glaucophyllum as source of 1,25-dihydroxycholecalciferol for poultry

1. Chemical characterisation of an extract of Solanum glaucophyllum (SG) leaves affirmed the predominant presence of 1,25-dihydroxycholecalciferol (1,25(OH)2D3) glycosides. The compound 1-(β-D-glucopyranosyl)-1α,25-dihydroxycholecalciferol was isolated for the first time from a natural source. 2. Vitamin D activity of the extract …

Bachmann, Autzen, Frey, Wehr, Rambeck, McCormack, Whitehead
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Scientific Paper Poultry Ruminant Swine Aqua

Vitamin D and the Immune System

It is now clear that vitamin D has important roles in addition to its classic effects on calcium and bone homeostasis. As the vitamin D receptor is expressed on immune cells (B cells, T cells, and antigen-presenting cells), and these immunologic cells are all capable of synthesizing the active vitamin D metabolite, vitamin D has the capability of acting in …
Aranow
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Article Poultry

Vitamin D3 metabolite 1,25(OH)2D3 and immune response in broilers

As antibiotic-free broiler production, often even including ionophore coccidiostats, is becoming more common, the immunocompetence of birds becomes increasingly important. One way to achieve this is to modulate and support the immune system to increase disease resistance of the animals.

Kathrin Bühler & Katia Pedrosa, Herbonis Animal Health GmbH
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