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Swine

Green Power for Pig Health and Welfare

This article explores the health and performance benefits of phytogenic feed ingredients in swine production. It highlights the role of Solanum glaucophyllum and other plant-based compounds in supporting vitamin D metabolism, improving piglet vitality, and promoting resilience in weaned piglets. The publication provides data and insights on the use of plant …
Kathrin Bühler, Sabrina Autzen, Clémence Messant
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Article Swine

Herbal vitamin D metabolite helps the farrowing process

With the increasing prolificity of sows it becomes essential to adjust nutrition to cover the needs of modern breeds. An important nutrient is vitamin D, as it is a key factor in calcium (Ca) and phosphorus (P) metabolism. The mineral requirement of sows is very high from the third part of gestation until the end of lactation.

by Katia Pedrosa, Dr Kathrin Buehler and Dr Jan Dirk Van der Klis, Herbonis Animal Health
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Article Swine

Vitamin D3 and its metabolites in sow fertility and performance

The number of piglets born alive, litter size at birth, and the number of weaned piglets per sow per year are reproductive traits with great economic impact on the profitability of pig production. Achieving high farrowing rates throughout the sow’s life, along with litter uniformity, are great challenges in high prolific sows.

Katia Pedrosa & Kathrin Bühler, Herbonis Animal Health GmbH
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Scientific Paper Swine

Tolerance to 1,25 dihydroxyvitamin D3 glycosides from Solanum glaucophyllum by the growing pig

Solanum glaucophyllum leaves contain high levels of glycosidically bound 1,25 dihydroxyvitamin D3, the most important vitamin D metabolite. The tolerance to this source was evaluated during six weeks with fifty weaned pigs fed increasing levels …

Schlegel, Guggisberg, Gutzwiller
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Scientific Paper Swine

Vitamin D and fertility: a systematic review

Background Vitamin D has been well-known for its function in maintaining calcium and phosphorus homeostasis and promoting bone mineralization. There is some evidence that in addition to sex steroid hormones, the classic regulators of human reproduction, …

Lerchbaum, Obermayer-Pietsch
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Scientific Paper Poultry Ruminant Swine Aqua

Vitamin D: Classic and Novel Actions

Background: Classically, vitamin D has been implicated in bone health by promoting calcium absorption in the gut and maintenance of serum calcium and phosphate concentrations, as well as by its action on bone growth and reorganization through the action of osteoblasts and osteoclasts cells.

Gil, Plaza-Diaz, Mesa
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Abstract Poultry Ruminant Swine Aqua

Consequences of genetic selection on metabolic regulation of skeletal health in broiler chickens

Improvements in broiler growth performance resulting from commercial selection are associated with poor skeletal health. Vitamin D3 plays an important role in Ca and P homeostasis and is essential for bone strength. Several studies have demonstrated that feeding biologically active metabolites of D3 [25(OH)D3 and 1,25(OH)2D3] can improve bone health.

Ellestad, Payne, Marhsal, Boothby
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Abstract Swine

Efficacy of orally administered Solbone®, an herbal source of metabolic active vitamin D, in piglets

The multiple biological effects of vitamin D are still the object of intensive research. It is critical not only for the homeostasis of calcium, phosphorus and magnesium but also for skeletal structure, immune response and performance. Pigs are able to synthesise sufficient vitamin D on their own when having outdoor access.

Dobenecker, Rambeck, Weiss, Senf, Renken, Kessler, Hinrichs, Bachmann, Bühler
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Abstract Swine

Herbal vitamin D metabolite facilitates parturition in sows

Introduction Modern pig farming is associated with high piglet mortality. The duration of farrowing is critical and has an impact on survival and subsequent thriving of the piglets. Since tedious labour caused by weak muscle tonus is linked to blood calcium level, it was thought that increasing Ca in the sows´ diet might improve the reproductive performance.
Bühler, Bachmann, Mayer, von Rosenberg, Rambeck
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Scientific Paper Poultry Ruminant Swine Aqua

1,25-Dihydroxyvitamin D3-glycoside of herbal origin exhibits delayed release pharmacokinetics when compared to its synthetic counterpart

Vitamin D requires two metabolic steps to become biologically active. In a first step 25-hydroxyvitamin D3 is formed, which acts as storage form. After a tightly controlled step in kidney the active metabolite 1,25-dihydroxyvitamin D3 (1,25(OH)2D3) is formed. Because kidney is the relevant metabolic organ for this conversion, 1,25(OH)2D3 needs …

1982 - Bachmann, Offord-Cavin, Phothirat, Horcajada, Romeis, Mathis
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Scientific Paper Poultry Ruminant Swine Aqua

Vitamin D and the Immune System

It is now clear that vitamin D has important roles in addition to its classic effects on calcium and bone homeostasis. As the vitamin D receptor is expressed on immune cells (B cells, T cells, and antigen-presenting cells), and these immunologic cells are all capable of synthesizing the active vitamin D metabolite, vitamin D has the capability of acting in …
Aranow
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