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Abstract Ruminant

The importance of colostrum during the first days of the piglet’s life

Colostrum, the ‘first milk’ produced by mammals in the first 24 to maximal 48 hours after giving birth, differs from the milk produced later during the lactation phase (mature milk). In general, colostrum has a higher protein and a lower lactose and fat content than mature milk.

International Pig Topics
Volume 38 Number 3

by Kathrin Buehler and Katia Pedrosa, Herbonis Animal Health GmbH
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Article Ruminant

Getting the balance right: the underestimated weight of dietary calcium

The macronutrient calcium (Ca) is mostly known for its crucial role in bone mineralisation and bone strength. Containing 99% of the body Ca reserves, the skeleton is the major storage site for Ca. Besides maintaining skeletal integrity, Ca is important for muscle contraction, neuronal transmission, intracellular signalling and many other functions.

by R&D and Technical Team, Herbonis Animal Health GmbH
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Scientific Paper Poultry Ruminant Swine Aqua

Vitamin D: Classic and Novel Actions

Background: Classically, vitamin D has been implicated in bone health by promoting calcium absorption in the gut and maintenance of serum calcium and phosphate concentrations, as well as by its action on bone growth and reorganization through the action of osteoblasts and osteoclasts cells.

Gil, Plaza-Diaz, Mesa
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Abstract Poultry Ruminant Swine Aqua

Consequences of genetic selection on metabolic regulation of skeletal health in broiler chickens

Improvements in broiler growth performance resulting from commercial selection are associated with poor skeletal health. Vitamin D3 plays an important role in Ca and P homeostasis and is essential for bone strength. Several studies have demonstrated that feeding biologically active metabolites of D3 [25(OH)D3 and 1,25(OH)2D3] can improve bone health.

Ellestad, Payne, Marhsal, Boothby
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Scientific Paper Poultry Ruminant Swine Aqua

1,25-Dihydroxyvitamin D3-glycoside of herbal origin exhibits delayed release pharmacokinetics when compared to its synthetic counterpart

Vitamin D requires two metabolic steps to become biologically active. In a first step 25-hydroxyvitamin D3 is formed, which acts as storage form. After a tightly controlled step in kidney the active metabolite 1,25-dihydroxyvitamin D3 (1,25(OH)2D3) is formed. Because kidney is the relevant metabolic organ for this conversion, 1,25(OH)2D3 needs …

1982 - Bachmann, Offord-Cavin, Phothirat, Horcajada, Romeis, Mathis
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Scientific Paper Poultry Ruminant Swine Aqua

Vitamin D and the Immune System
It is now clear that vitamin D has important roles in addition to its classic effects on calcium and bone homeostasis. As the vitamin D receptor is expressed on immune cells (B cells, T cells, and antigen-presenting cells), and these immunologic cells are all capable of synthesizing the active vitamin D metabolite, vitamin D has the capability of acting in …
Aranow
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